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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMF1 All Species: 21.52
Human Site: S925 Identified Species: 29.58
UniProt: P82094 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P82094 NP_009045.2 1093 122842 S925 E K E R K P F S V S S T P T M
Chimpanzee Pan troglodytes XP_526227 1093 122795 S925 E K E R K P F S V S S T P T M
Rhesus Macaque Macaca mulatta XP_001088711 1092 122828 S924 E K E R K P F S V S S T P T M
Dog Lupus familis XP_533766 1089 122761 F921 K E K E R K P F S V S S T P T
Cat Felis silvestris
Mouse Mus musculus B9EKI3 1091 121796 S923 E K D H K L F S V C S T P T M
Rat Rattus norvegicus NP_446123 1093 121882 S925 E K E H K P F S V S S T P T M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510334 1106 124384 S938 F P F S T M E S V S S T P T L
Chicken Gallus gallus O42184 1433 161009 V1196 K L E E E R S V L N N Q L L E
Frog Xenopus laevis Q5PQ23 649 75475 D491 E R G R L E R D S L L E K L H
Zebra Danio Brachydanio rerio NP_001003522 1136 126986 A968 L S V T D A P A S S T P S L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572360 933 103794 E774 V D D S G S N E E A L G G M I
Honey Bee Apis mellifera XP_394037 1326 150590 A1040 L L K R L E A A E A R S E E L
Nematode Worm Caenorhab. elegans P02566 1966 225108 A1559 L Q H A L D E A E A A L E A E
Sea Urchin Strong. purpuratus XP_785821 1176 131318 N1009 R L Q Q A E D N S G S P S P S
Poplar Tree Populus trichocarpa XP_002303293 975 109171 A817 L T R K L S S A S S L G S I E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WVL7 956 108335 G798 Q N S A F E N G S L P R K L S
Baker's Yeast Sacchar. cerevisiae P47166 707 81153 S549 D R K N V D F S I D D I P E E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.5 93.1 N.A. 87.2 86.7 N.A. 81.2 21.7 22.6 59.7 N.A. 26.1 23.9 21 37.7
Protein Similarity: 100 99.4 99.1 96.1 N.A. 92.5 92 N.A. 88.3 39.9 37.3 74.6 N.A. 45.8 44.9 36.6 56.8
P-Site Identity: 100 100 100 6.6 N.A. 73.3 93.3 N.A. 46.6 6.6 13.3 6.6 N.A. 0 6.6 0 6.6
P-Site Similarity: 100 100 100 40 N.A. 80 93.3 N.A. 53.3 40 20 20 N.A. 20 40 26.6 26.6
Percent
Protein Identity: 25.8 N.A. N.A. 27.1 21.1 N.A.
Protein Similarity: 47.2 N.A. N.A. 45.4 39.4 N.A.
P-Site Identity: 6.6 N.A. N.A. 0 20 N.A.
P-Site Similarity: 20 N.A. N.A. 6.6 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 12 6 6 6 24 0 18 6 0 0 6 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % C
% Asp: 6 6 12 0 6 12 6 6 0 6 6 0 0 0 0 % D
% Glu: 36 6 30 12 6 24 12 6 18 0 0 6 12 12 24 % E
% Phe: 6 0 6 0 6 0 36 6 0 0 0 0 0 0 0 % F
% Gly: 0 0 6 0 6 0 0 6 0 6 0 12 6 0 0 % G
% His: 0 0 6 12 0 0 0 0 0 0 0 0 0 0 6 % H
% Ile: 0 0 0 0 0 0 0 0 6 0 0 6 0 6 6 % I
% Lys: 12 30 18 6 30 6 0 0 0 0 0 0 12 0 0 % K
% Leu: 24 18 0 0 24 6 0 0 6 12 18 6 6 24 12 % L
% Met: 0 0 0 0 0 6 0 0 0 0 0 0 0 6 30 % M
% Asn: 0 6 0 6 0 0 12 6 0 6 6 0 0 0 0 % N
% Pro: 0 6 0 0 0 24 12 0 0 0 6 12 42 12 0 % P
% Gln: 6 6 6 6 0 0 0 0 0 0 0 6 0 0 0 % Q
% Arg: 6 12 6 30 6 6 6 0 0 0 6 6 0 0 0 % R
% Ser: 0 6 6 12 0 12 12 42 36 42 48 12 18 0 18 % S
% Thr: 0 6 0 6 6 0 0 0 0 0 6 36 6 36 6 % T
% Val: 6 0 6 0 6 0 0 6 36 6 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _